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• Activity deltas table
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Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 1.978

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_21361901	8.905		MKRN3	makorin ring finger protein 3
chr6_-_168219380	7.077	NM_001122841	FRMD1	FERM domain containing 1
chr7_+_50318801	5.580		IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr10_-_11976704	5.173		LOC219731	hypothetical LOC219731
chr12_-_53153613	4.913		GTSF1	gametocyte specific factor 1
chr12_-_53153639	4.844	NM_144594	GTSF1	gametocyte specific factor 1
chr7_+_106292932	4.548		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr12_-_70343656	4.497
chr7_+_106293112	4.441	NM_002649	PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr2_+_169367345	4.370	NM_001039724 NM_001171632 NM_052946	NOSTRIN	nitric oxide synthase trafficker
chr22_+_20350272	4.361	NM_014337 NM_148175 NM_148176	PPIL2	peptidylprolyl isomerase (cyclophilin)-like 2
chr7_+_106292975	4.264		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr22_+_17799341	4.164		MRPL40	mitochondrial ribosomal protein L40
chrX_+_153428755	4.111	NM_001099857 NM_001145255	IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chrX_-_153428621	4.073		G6PD	glucose-6-phosphate dehydrogenase
chr2_+_113648036	4.057		PSD4	pleckstrin and Sec7 domain containing 4
chr6_-_33347563	4.042	NM_022553	VPS52	vacuolar protein sorting 52 homolog (S. cerevisiae)
chr6_+_33347776	3.782	NM_022551	RPS18	ribosomal protein S18
chr22_+_19191898	3.725		MED15	mediator complex subunit 15
chr9_-_133141726	3.713	NM_033387	FAM78A	family with sequence similarity 78, member A
chr22_+_19191886	3.652		MED15	mediator complex subunit 15
chr22_+_19191884	3.645	NM_001003891 NM_015889	MED15	mediator complex subunit 15
chr22_+_19191875	3.638		MED15	mediator complex subunit 15
chr6_+_33347833	3.620		RPS18	ribosomal protein S18
chr22_+_19191859	3.616		MED15	mediator complex subunit 15
chrX_-_153428968	3.600	NM_001042351	G6PD	glucose-6-phosphate dehydrogenase
chr22_-_17799177	3.473		HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr22_+_19191964	3.467		MED15	mediator complex subunit 15
chr1_+_40496508	3.439		ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr8_-_38153325	3.435		LSM1	LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr22_-_17799215	3.386	NM_003325	HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chrX_-_153632355	3.380	NM_001081573 NM_080612	GAB3	GRB2-associated binding protein 3
chr2_+_113648020	3.372	NM_012455	PSD4	pleckstrin and Sec7 domain containing 4
chrX_-_130792297	3.357		LOC286467	hypothetical LOC286467
chr5_-_137906767	3.357		ETF1	eukaryotic translation termination factor 1
chrX_+_153429022	3.353		IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr12_-_70343790	3.324		ZFC3H1	zinc finger, C3H1-type containing
chr8_+_38153453	3.273		BAG4	BCL2-associated athanogene 4
chr22_-_17798998	3.267		HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr1_+_118273869	3.247		WDR3	WD repeat domain 3
chr1_+_40496494	3.246		ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr22_-_19543069	3.241	NM_058004	PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr8_-_38153369	3.207		LSM1	LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr21_-_32906528	3.207		C21orf59	chromosome 21 open reading frame 59
chr1_-_203867402	3.178		ELK4	ELK4, ETS-domain protein (SRF accessory protein 1)
chr1_+_40496451	3.173		ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr6_+_160068531	3.154		WTAP	Wilms tumor 1 associated protein
chr8_+_38153514	3.137		BAG4	BCL2-associated athanogene 4
chr1_+_40496317	3.128	NM_005857	ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr1_-_38046270	3.118		YRDC	yrdC domain containing (E. coli)
chr7_-_128482354	3.118		TNPO3	transportin 3
chr1_+_118273887	3.090	NM_006784	WDR3	WD repeat domain 3
chr7_+_98844480	3.068	NM_003910	BUD31	BUD31 homolog (S. cerevisiae)
chr7_-_98844151	3.063		PDAP1	PDGFA associated protein 1
chr11_+_60954096	3.022		SDHAF2	succinate dehydrogenase complex assembly factor 2
chrX_+_153429042	3.013		IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr9_-_130124820	3.008		TRUB2	TruB pseudouridine (psi) synthase homolog 2 (E. coli)
chr7_+_75515341	3.008		MDH2	malate dehydrogenase 2, NAD (mitochondrial)
chr7_-_128482059	3.005		TNPO3	transportin 3
chr17_+_24013320	2.993		SUPT6H	suppressor of Ty 6 homolog (S. cerevisiae)
chr10_-_12278026	2.990	NM_014142	NUDT5	nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr22_+_19543248	2.986	NM_004782	SNAP29	synaptosomal-associated protein, 29kDa
chr1_+_40496425	2.980		ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr19_+_17723285	2.975	NM_001161359 NM_015122	FCHO1	FCH domain only 1
chr1_-_184610953	2.966		TPR	translocated promoter region (to activated MET oncogene)
chr6_+_160068553	2.963		WTAP	Wilms tumor 1 associated protein
chr1_+_38046005	2.947		C1orf122	chromosome 1 open reading frame 122
chr1_+_181708235	2.941		SMG7	Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr6_+_160068544	2.933		WTAP	Wilms tumor 1 associated protein
chr9_+_130124566	2.932	NM_016035	COQ4	coenzyme Q4 homolog (S. cerevisiae)
chr1_+_36169260	2.924	NM_024852 NM_177422	EIF2C3	eukaryotic translation initiation factor 2C, 3
chr5_+_36912656	2.920		NIPBL	Nipped-B homolog (Drosophila)
chr10_+_12278185	2.916		CDC123	cell division cycle 123 homolog (S. cerevisiae)
chr16_-_1999760	2.910	NM_178167	ZNF598	zinc finger protein 598
chr6_+_160130968	2.899		MRPL18	mitochondrial ribosomal protein L18
chr22_-_19543099	2.883		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr7_-_99355085	2.865	NM_033017 NM_033091	TRIM4	tripartite motif containing 4
chr3_-_151746821	2.858		SERP1	stress-associated endoplasmic reticulum protein 1
chr7_-_128482417	2.812	NM_001191028 NM_012470	TNPO3	transportin 3
chr22_+_19543350	2.786		SNAP29	synaptosomal-associated protein, 29kDa
chr1_+_38046055	2.783	NM_001142726 NM_198446	C1orf122	chromosome 1 open reading frame 122
chr9_-_122595475	2.778	NM_012164	FBXW2	F-box and WD repeat domain containing 2
chrX_-_131179598	2.772	NM_021183	RAP2C	RAP2C, member of RAS oncogene family
chr9_+_130124873	2.762		COQ4	coenzyme Q4 homolog (S. cerevisiae)
chr5_+_65258316	2.758		ERBB2IP	erbb2 interacting protein
chr1_-_38046433	2.748		YRDC	yrdC domain containing (E. coli)
chr6_-_33347417	2.747		VPS52	vacuolar protein sorting 52 homolog (S. cerevisiae)
chr10_+_12278213	2.728		CDC123	cell division cycle 123 homolog (S. cerevisiae)
chr1_+_20385164	2.720	NM_152376	UBXN10	UBX domain protein 10
chrX_-_153428196	2.702		G6PD	glucose-6-phosphate dehydrogenase
chr5_-_137906800	2.683		ETF1	eukaryotic translation termination factor 1
chr16_+_29581783	2.678	NM_001030288	SPN	sialophorin
chr3_+_198153865	2.665		LOC152217	hypothetical LOC152217
chr8_+_38153223	2.659	NM_004874	BAG4	BCL2-associated athanogene 4
chr3_+_47004457	2.641		NBEAL2	neurobeachin-like 2
chr16_-_67930974	2.637	NM_032382	COG8	component of oligomeric golgi complex 8
chr11_-_60954031	2.635	NM_001136040 NM_001142565	CPSF7	cleavage and polyadenylation specific factor 7, 59kDa
chr1_+_202647097	2.622
chr3_-_151746970	2.600	NM_014445	SERP1	stress-associated endoplasmic reticulum protein 1
chr1_+_244796426	2.591		CNST	consortin, connexin sorting protein
chr1_+_158579685	2.575	NM_015331	NCSTN	nicastrin
chr11_-_46678736	2.567		ARHGAP1	Rho GTPase activating protein 1
chr7_-_98844106	2.566		PDAP1	PDGFA associated protein 1
chr11_-_46678691	2.564	NM_004308	ARHGAP1	Rho GTPase activating protein 1
chr12_-_70343943	2.563	NM_144982	ZFC3H1	zinc finger, C3H1-type containing
chr1_+_244796347	2.561		CNST	consortin, connexin sorting protein
chr10_+_12277935	2.542	NM_006023	CDC123	cell division cycle 123 homolog (S. cerevisiae)
chr5_-_137906789	2.541		ETF1	eukaryotic translation termination factor 1
chr19_+_10402334	2.535	NM_001111308	PDE4A	phosphodiesterase 4A, cAMP-specific
chr7_-_99355065	2.535		TRIM4	tripartite motif containing 4
chr7_-_75515253	2.527	NM_016086	STYXL1	serine/threonine/tyrosine interacting-like 1
chr1_-_40496161	2.523
chr1_+_244796441	2.516		CNST	consortin, connexin sorting protein
chr7_+_75515355	2.515		MDH2	malate dehydrogenase 2, NAD (mitochondrial)
chr6_+_160068598	2.479	NM_152857	WTAP	Wilms tumor 1 associated protein
chr6_+_160068475	2.467		WTAP	Wilms tumor 1 associated protein
chr16_+_29582065	2.459		SPN	sialophorin
chr9_-_122595349	2.457		FBXW2	F-box and WD repeat domain containing 2
chr22_-_19543012	2.457		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr1_-_158579680	2.454		COPA	coatomer protein complex, subunit alpha
chr21_+_45184394	2.452
chr2_-_55131202	2.451	NM_020532 NM_153828 NM_207520	RTN4	reticulon 4
chr5_-_945872	2.450		BRD9	bromodomain containing 9
chr3_+_151747204	2.449	NM_032025	EIF2A	eukaryotic translation initiation factor 2A, 65kDa
chr1_+_158579796	2.449		NCSTN	nicastrin
chr6_-_153365532	2.434		MTRF1L	mitochondrial translational release factor 1-like
chr4_-_140224794	2.431		ELF2	E74-like factor 2 (ets domain transcription factor)
chr3_-_151746924	2.426		SERP1	stress-associated endoplasmic reticulum protein 1
chr5_-_40871040	2.426		RPL37 SNORD72	ribosomal protein L37 small nucleolar RNA, C/D box 72
chr3_-_198153770	2.420	NM_001042540 NM_007362	NCBP2	nuclear cap binding protein subunit 2, 20kDa
chr16_+_29582069	2.415	NM_003123	SPN	sialophorin
chr1_-_164004611	2.412		TMCO1	transmembrane and coiled-coil domains 1
chr1_-_38046410	2.409		YRDC	yrdC domain containing (E. coli)
chr2_+_65308332	2.402	NM_001005386 NM_005722	ACTR2	ARP2 actin-related protein 2 homolog (yeast)
chr1_-_158579653	2.400		COPA	coatomer protein complex, subunit alpha
chr12_+_70343943	2.395	NM_031435	THAP2	THAP domain containing, apoptosis associated protein 2
chr1_-_2312856	2.394		MORN1	MORN repeat containing 1
chr20_+_48560327	2.393		PTPN1	protein tyrosine phosphatase, non-receptor type 1
chr7_+_75515385	2.392		MDH2	malate dehydrogenase 2, NAD (mitochondrial)
chr1_-_164004730	2.387	NM_019026	TMCO1	transmembrane and coiled-coil domains 1
chr1_-_158579583	2.373
chr16_-_1999796	2.362		ZNF598	zinc finger protein 598
chr5_-_137906707	2.360		ETF1	eukaryotic translation termination factor 1
chr11_-_46678715	2.358		ARHGAP1	Rho GTPase activating protein 1
chr1_+_40279036	2.351		CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)
chr1_-_51198417	2.348		FAF1	Fas (TNFRSF6) associated factor 1
chr1_-_148818629	2.343		MCL1	myeloid cell leukemia sequence 1 (BCL2-related)
chr9_-_37775064	2.339	NM_016042 NM_001002269	EXOSC3	exosome component 3
chr6_-_153365542	2.338		MTRF1L	mitochondrial translational release factor 1-like
chr18_+_3252184	2.337		MYL12B	myosin, light chain 12B, regulatory
chr1_-_17637639	2.321	NM_001136204	RCC2	regulator of chromosome condensation 2
chr19_-_17349096	2.320	NM_031310	PLVAP	plasmalemma vesicle associated protein
chr11_+_118394350	2.320	NM_016146	TRAPPC4	trafficking protein particle complex 4
chr10_+_12278200	2.316		CDC123	cell division cycle 123 homolog (S. cerevisiae)
chr1_-_51198383	2.313		FAF1	Fas (TNFRSF6) associated factor 1
chr5_-_40871082	2.313	NM_000997	RPL37	ribosomal protein L37
chr5_+_36912595	2.305	NM_015384 NM_133433	NIPBL	Nipped-B homolog (Drosophila)
chr6_+_170705345	2.304	NM_001172085 NM_003194	TBP	TATA box binding protein
chr20_+_48560326	2.297		PTPN1	protein tyrosine phosphatase, non-receptor type 1
chr2_+_68855436	2.290	NM_001166276 NM_014882	ARHGAP25	Rho GTPase activating protein 25
chr9_-_37775052	2.285		EXOSC3	exosome component 3
chr9_-_37775013	2.281		EXOSC3	exosome component 3
chr1_+_38046073	2.281		C1orf122	chromosome 1 open reading frame 122
chr9_-_130124317	2.280	NM_015679	TRUB2	TruB pseudouridine (psi) synthase homolog 2 (E. coli)
chr7_-_99355051	2.279		TRIM4	tripartite motif containing 4
chr3_-_197549640	2.278	NM_138461	TM4SF19	transmembrane 4 L six family member 19
chr6_+_46763570	2.274	NM_001010870 NM_001168359	TDRD6	tudor domain containing 6
chr8_-_102032529	2.259	NM_001135700 NM_001135701	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr3_-_197549588	2.258		TM4SF19	transmembrane 4 L six family member 19
chr22_-_17846621	2.257		UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr8_-_102032852	2.255		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr5_-_945914	2.241		BRD9	bromodomain containing 9
chr8_-_68136881	2.234		COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
chr2_-_174968595	2.233	NM_004882	CIR1	corepressor interacting with RBPJ, 1
chr7_+_107997544	2.231	NM_012328	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr1_-_17637576	2.227		RCC2	regulator of chromosome condensation 2
chr3_-_187025501	2.216	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr21_+_44256630	2.216	NM_003274	TRAPPC10	trafficking protein particle complex 10
chr1_+_181708068	2.207	NM_001174061 NM_173156 NM_201568 NM_201569	SMG7	Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr2_+_98591516	2.174		UNC50	unc-50 homolog (C. elegans)
chr6_-_31728447	2.174	NM_004639 NM_080702 NM_080703	BAG6	BCL2-associated athanogene 6
chr1_-_201194040	2.170		ADIPOR1	adiponectin receptor 1
chr19_-_7607852	2.166
chrX_+_153908426	2.165		FUNDC2	FUN14 domain containing 2
chr20_+_48560264	2.165	NM_002827	PTPN1	protein tyrosine phosphatase, non-receptor type 1
chr6_-_153365480	2.162		MTRF1L	mitochondrial translational release factor 1-like
chr17_+_46585928	2.159		NME1	non-metastatic cells 1, protein (NM23A) expressed in
chr16_-_70400232	2.157		AP1G1	adaptor-related protein complex 1, gamma 1 subunit
chr9_-_99435782	2.155	NM_139246	TSTD2	thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr21_-_37561495	2.154	NM_006052	DSCR3	Down syndrome critical region gene 3
chr22_+_18485095	2.148		RANBP1	RAN binding protein 1
chr1_-_184610796	2.147		TPR	translocated promoter region (to activated MET oncogene)
chr6_-_43651745	2.143	NM_020750	XPO5	exportin 5
chr1_+_244796261	2.140	NM_001139459 NM_152609	CNST	consortin, connexin sorting protein
chr1_-_244796169	2.133	NM_022366	TFB2M	transcription factor B2, mitochondrial
chr7_+_107997527	2.132		DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr10_-_12277846	2.117		NUDT5	nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr6_+_43651855	2.113	NM_006502	POLH	polymerase (DNA directed), eta
chr15_+_21361546	2.113	NM_005664	MKRN3	makorin ring finger protein 3
chr7_+_120416680	2.113	NM_001105533	C7orf58	chromosome 7 open reading frame 58

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.44	2.39e-55	GO:0044260	cellular macromolecule metabolic process
1.36	6.17e-45	GO:0043170	macromolecule metabolic process
1.56	1.46e-37	GO:0090304	nucleic acid metabolic process
1.48	1.33e-36	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27	3.66e-36	GO:0044237	cellular metabolic process
1.59	6.72e-34	GO:0010467	gene expression
1.61	1.39e-33	GO:0016070	RNA metabolic process
1.24	4.24e-29	GO:0044238	primary metabolic process
2.08	6.47e-29	GO:0016071	mRNA metabolic process
1.45	3.69e-28	GO:0044267	cellular protein metabolic process
1.21	2.32e-27	GO:0008152	metabolic process
2.20	4.31e-27	GO:0016032	viral reproduction
1.94	8.25e-27	GO:0006396	RNA processing
1.37	6.71e-26	GO:0034641	cellular nitrogen compound metabolic process
1.36	2.62e-24	GO:0006807	nitrogen compound metabolic process
2.12	4.11e-22	GO:0006397	mRNA processing
2.27	5.20e-22	GO:0008380	RNA splicing
1.50	6.11e-22	GO:0009059	macromolecule biosynthetic process
1.50	2.30e-21	GO:0034645	cellular macromolecule biosynthetic process
2.53	6.50e-21	GO:0000375	RNA splicing, via transesterification reactions
2.52	3.47e-20	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.52	3.47e-20	GO:0000398	nuclear mRNA splicing, via spliceosome
1.34	1.57e-19	GO:0019538	protein metabolic process
1.34	7.30e-18	GO:0071841	cellular component organization or biogenesis at cellular level
2.13	1.11e-17	GO:0006412	translation
1.29	2.05e-17	GO:0071840	cellular component organization or biogenesis
2.40	5.23e-17	GO:0022613	ribonucleoprotein complex biogenesis
1.77	8.88e-17	GO:0009057	macromolecule catabolic process
1.83	1.51e-16	GO:0044265	cellular macromolecule catabolic process
2.32	4.91e-16	GO:0071843	cellular component biogenesis at cellular level
1.60	8.94e-15	GO:0045184	establishment of protein localization
1.61	9.13e-15	GO:0015031	protein transport
1.51	3.49e-14	GO:0044248	cellular catabolic process
1.10	3.87e-14	GO:0009987	cellular process
1.61	1.48e-13	GO:0046907	intracellular transport
1.26	1.93e-12	GO:0016043	cellular component organization
1.69	2.72e-12	GO:0000278	mitotic cell cycle
1.30	2.90e-12	GO:0071842	cellular component organization at cellular level
1.50	2.95e-12	GO:0007049	cell cycle
1.88	3.26e-12	GO:0030163	protein catabolic process
1.73	3.47e-12	GO:0006974	response to DNA damage stimulus
1.92	3.93e-12	GO:0051603	proteolysis involved in cellular protein catabolic process
1.31	5.22e-12	GO:0044249	cellular biosynthetic process
1.89	9.33e-12	GO:0044257	cellular protein catabolic process
1.43	1.55e-11	GO:0033036	macromolecule localization
1.38	1.67e-11	GO:0006996	organelle organization
1.92	1.82e-11	GO:0006511	ubiquitin-dependent protein catabolic process
1.89	3.03e-11	GO:0043632	modification-dependent macromolecule catabolic process
1.40	3.26e-11	GO:0009056	catabolic process
1.89	4.32e-11	GO:0019941	modification-dependent protein catabolic process
1.29	4.55e-11	GO:0009058	biosynthetic process
1.47	5.93e-11	GO:0008104	protein localization
2.43	8.32e-11	GO:0042254	ribosome biogenesis
1.58	2.48e-10	GO:0022403	cell cycle phase
1.52	4.98e-10	GO:0033554	cellular response to stress
2.66	5.86e-10	GO:0006415	translational termination
1.52	1.32e-09	GO:0022402	cell cycle process
1.47	1.66e-09	GO:0032774	RNA biosynthetic process
1.67	1.79e-09	GO:0034621	cellular macromolecular complex subunit organization
2.19	1.98e-09	GO:0022415	viral reproductive process
2.65	2.23e-09	GO:0019080	viral genome expression
2.65	2.23e-09	GO:0019083	viral transcription
2.49	2.83e-09	GO:0006414	translational elongation
1.80	3.27e-09	GO:0070647	protein modification by small protein conjugation or removal
2.73	4.51e-09	GO:0006353	transcription termination, DNA-dependent
2.51	5.89e-09	GO:0043241	protein complex disassembly
2.51	5.89e-09	GO:0043624	cellular protein complex disassembly
1.57	6.70e-09	GO:0051726	regulation of cell cycle
1.90	7.49e-09	GO:0016567	protein ubiquitination
1.49	8.38e-09	GO:0043933	macromolecular complex subunit organization
1.42	9.22e-09	GO:0051649	establishment of localization in cell
2.39	1.14e-08	GO:0032984	macromolecular complex disassembly
2.39	1.14e-08	GO:0034623	cellular macromolecular complex disassembly
1.86	1.37e-08	GO:0032446	protein modification by small protein conjugation
1.81	1.84e-08	GO:0051325	interphase
1.81	2.78e-08	GO:0051329	interphase of mitotic cell cycle
1.38	2.84e-08	GO:0051641	cellular localization
2.21	3.73e-08	GO:0019058	viral infectious cycle
1.93	6.27e-08	GO:0071156	regulation of cell cycle arrest
1.74	7.00e-08	GO:0010564	regulation of cell cycle process
1.38	7.98e-08	GO:0044085	cellular component biogenesis
1.94	9.80e-08	GO:0000075	cell cycle checkpoint
1.55	1.20e-07	GO:0071822	protein complex subunit organization
3.10	5.41e-07	GO:0006369	termination of RNA polymerase II transcription
2.43	7.00e-07	GO:0071826	ribonucleoprotein complex subunit organization
2.40	8.11e-07	GO:0006364	rRNA processing
1.78	8.86e-07	GO:0010608	posttranscriptional regulation of gene expression
1.28	1.02e-06	GO:0043412	macromolecule modification
1.79	1.03e-06	GO:0007346	regulation of mitotic cell cycle
2.01	1.85e-06	GO:0010498	proteasomal protein catabolic process
2.01	1.85e-06	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
2.20	2.40e-06	GO:0051320	S phase
2.32	2.46e-06	GO:0016072	rRNA metabolic process
2.41	2.50e-06	GO:0051168	nuclear export
2.20	3.51e-06	GO:0000084	S phase of mitotic cell cycle
2.41	3.63e-06	GO:0022618	ribonucleoprotein complex assembly
2.20	5.12e-06	GO:0000077	DNA damage checkpoint
2.04	5.90e-06	GO:0000082	G1/S transition of mitotic cell cycle
2.10	6.00e-06	GO:0007093	mitotic cell cycle checkpoint
1.90	7.14e-06	GO:0022411	cellular component disassembly
1.90	7.14e-06	GO:0071845	cellular component disassembly at cellular level
2.15	8.32e-06	GO:0031570	DNA integrity checkpoint
1.27	8.49e-06	GO:0006464	protein modification process
2.13	8.50e-06	GO:0031018	endocrine pancreas development
2.35	1.00e-05	GO:2000045	regulation of G1/S transition of mitotic cell cycle
1.64	1.03e-05	GO:0044419	interspecies interaction between organisms
1.73	1.26e-05	GO:0034660	ncRNA metabolic process
1.64	1.84e-05	GO:0006281	DNA repair
2.36	2.13e-05	GO:0000216	M/G1 transition of mitotic cell cycle
2.36	2.13e-05	GO:0031575	mitotic cell cycle G1/S transition checkpoint
2.36	2.13e-05	GO:0071779	G1/S transition checkpoint
1.59	2.54e-05	GO:0006886	intracellular protein transport
1.48	2.57e-05	GO:0006259	DNA metabolic process
2.06	2.68e-05	GO:0006403	RNA localization
1.98	3.48e-05	GO:0031016	pancreas development
2.33	5.08e-05	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.30	5.60e-05	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.05	5.65e-05	GO:0050657	nucleic acid transport
2.05	5.65e-05	GO:0050658	RNA transport
2.05	5.65e-05	GO:0051236	establishment of RNA localization
2.46	7.24e-05	GO:0071158	positive regulation of cell cycle arrest
2.30	8.19e-05	GO:0051443	positive regulation of ubiquitin-protein ligase activity
2.20	1.06e-04	GO:0051438	regulation of ubiquitin-protein ligase activity
1.64	1.09e-04	GO:0048285	organelle fission
2.30	1.20e-04	GO:0006354	transcription elongation, DNA-dependent
2.25	1.40e-04	GO:0051351	positive regulation of ligase activity
2.38	1.41e-04	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
1.78	1.46e-04	GO:0006457	protein folding
2.34	1.59e-04	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.15	1.66e-04	GO:0051340	regulation of ligase activity
2.31	1.75e-04	GO:0000209	protein polyubiquitination
1.83	1.85e-04	GO:0051169	nuclear transport
2.38	2.06e-04	GO:0006405	RNA export from nucleus
1.36	2.58e-04	GO:0008219	cell death
1.82	2.61e-04	GO:0006913	nucleocytoplasmic transport
2.43	2.61e-04	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.43	2.61e-04	GO:0072395	signal transduction involved in cell cycle checkpoint
2.43	2.61e-04	GO:0072401	signal transduction involved in DNA integrity checkpoint
2.43	2.61e-04	GO:0072404	signal transduction involved in G1/S transition checkpoint
2.43	2.61e-04	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
2.43	2.61e-04	GO:0072422	signal transduction involved in DNA damage checkpoint
2.43	2.61e-04	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.43	2.61e-04	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
1.47	2.63e-04	GO:0070727	cellular macromolecule localization
2.28	2.79e-04	GO:0031123	RNA 3'-end processing
2.35	3.39e-04	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.04	3.62e-04	GO:0051028	mRNA transport
2.44	3.80e-04	GO:0006406	mRNA export from nucleus
1.36	4.10e-04	GO:0016265	death
1.72	4.62e-04	GO:0009261	ribonucleotide catabolic process
1.38	4.84e-04	GO:0016192	vesicle-mediated transport
1.47	5.09e-04	GO:0034613	cellular protein localization
1.90	5.11e-04	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.62	6.03e-04	GO:0000280	nuclear division
1.62	6.03e-04	GO:0006366	transcription from RNA polymerase II promoter
1.62	6.03e-04	GO:0007067	mitosis
1.60	7.36e-04	GO:0000087	M phase of mitotic cell cycle
1.82	8.38e-04	GO:0006417	regulation of translation
2.00	1.05e-03	GO:0031398	positive regulation of protein ubiquitination
1.70	1.21e-03	GO:0009203	ribonucleoside triphosphate catabolic process
1.70	1.21e-03	GO:0009207	purine ribonucleoside triphosphate catabolic process
1.34	1.22e-03	GO:0006351	transcription, DNA-dependent
1.70	1.32e-03	GO:0033365	protein localization to organelle
1.66	1.36e-03	GO:0006195	purine nucleotide catabolic process
2.25	1.37e-03	GO:0051352	negative regulation of ligase activity
2.25	1.37e-03	GO:0051444	negative regulation of ubiquitin-protein ligase activity
1.69	1.39e-03	GO:0009154	purine ribonucleotide catabolic process
1.69	1.52e-03	GO:0009146	purine nucleoside triphosphate catabolic process
1.16	1.77e-03	GO:0060255	regulation of macromolecule metabolic process
1.64	2.34e-03	GO:0072523	purine-containing compound catabolic process
1.37	2.42e-03	GO:0065003	macromolecular complex assembly
2.32	2.52e-03	GO:0006368	transcription elongation from RNA polymerase II promoter
1.70	2.73e-03	GO:0006605	protein targeting
2.28	2.75e-03	GO:0031124	mRNA 3'-end processing
1.67	2.97e-03	GO:0009143	nucleoside triphosphate catabolic process
1.37	3.19e-03	GO:0006915	apoptosis
1.36	4.17e-03	GO:0012501	programmed cell death
2.81	4.77e-03	GO:0000245	spliceosome assembly
1.70	5.37e-03	GO:0034470	ncRNA processing
1.46	6.95e-03	GO:0000279	M phase
2.18	6.98e-03	GO:0072594	establishment of protein localization to organelle
2.04	7.29e-03	GO:0030330	DNA damage response, signal transduction by p53 class mediator
1.29	8.51e-03	GO:0032268	regulation of cellular protein metabolic process
1.78	9.76e-03	GO:0031396	regulation of protein ubiquitination
1.58	1.04e-02	GO:0009166	nucleotide catabolic process
2.38	1.04e-02	GO:0050434	positive regulation of viral transcription
1.70	1.46e-02	GO:0043687	post-translational protein modification
1.62	1.56e-02	GO:0048011	nerve growth factor receptor signaling pathway
1.47	1.80e-02	GO:0034622	cellular macromolecular complex assembly
2.29	1.87e-02	GO:0006521	regulation of cellular amino acid metabolic process
2.79	1.89e-02	GO:0000387	spliceosomal snRNP assembly
1.88	2.21e-02	GO:0090068	positive regulation of cell cycle process
1.51	2.62e-02	GO:0009141	nucleoside triphosphate metabolic process
1.52	2.73e-02	GO:0009144	purine nucleoside triphosphate metabolic process
1.77	2.90e-02	GO:0048193	Golgi vesicle transport
1.96	2.96e-02	GO:0031397	negative regulation of protein ubiquitination
1.26	3.02e-02	GO:0051246	regulation of protein metabolic process
1.52	3.02e-02	GO:0009205	purine ribonucleoside triphosphate metabolic process
1.31	3.07e-02	GO:0006508	proteolysis
2.17	3.22e-02	GO:0070925	organelle assembly
1.51	3.57e-02	GO:0009199	ribonucleoside triphosphate metabolic process
1.26	3.59e-02	GO:0022607	cellular component assembly
2.87	3.66e-02	GO:0008334	histone mRNA metabolic process
1.85	3.96e-02	GO:0042770	signal transduction in response to DNA damage
1.46	4.07e-02	GO:0051301	cell division
2.20	4.55e-02	GO:0046782	regulation of viral transcription
2.03	4.79e-02	GO:0007173	epidermal growth factor receptor signaling pathway
2.05	4.86e-02	GO:0006302	double-strand break repair

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.19	1.74e-70	GO:0044424	intracellular part
1.18	4.02e-68	GO:0005622	intracellular
1.25	2.22e-61	GO:0043227	membrane-bounded organelle
1.25	7.88e-61	GO:0043231	intracellular membrane-bounded organelle
1.22	7.66e-59	GO:0043229	intracellular organelle
1.22	1.02e-58	GO:0043226	organelle
1.60	4.14e-45	GO:0044428	nuclear part
1.58	8.09e-44	GO:0070013	intracellular organelle lumen
1.32	1.77e-43	GO:0005634	nucleus
1.56	3.71e-43	GO:0031974	membrane-enclosed lumen
2.30	8.19e-43	GO:0030529	ribonucleoprotein complex
1.56	2.20e-42	GO:0043233	organelle lumen
1.31	1.99e-41	GO:0044446	intracellular organelle part
1.63	1.71e-40	GO:0031981	nuclear lumen
1.30	5.04e-40	GO:0044422	organelle part
1.19	5.76e-32	GO:0005737	cytoplasm
1.37	8.81e-31	GO:0032991	macromolecular complex
1.61	1.86e-26	GO:0005654	nucleoplasm
1.22	2.50e-23	GO:0044444	cytoplasmic part
1.87	9.32e-19	GO:0005730	nucleolus
2.63	9.83e-17	GO:0005681	spliceosomal complex
1.37	5.81e-16	GO:0005829	cytosol
1.31	1.38e-15	GO:0043228	non-membrane-bounded organelle
1.31	1.38e-15	GO:0043232	intracellular non-membrane-bounded organelle
2.28	1.72e-14	GO:0005840	ribosome
2.79	2.61e-11	GO:0071013	catalytic step 2 spliceosome
1.55	9.75e-11	GO:0044451	nucleoplasm part
1.25	1.00e-10	GO:0043234	protein complex
2.10	1.73e-08	GO:0044445	cytosolic part
1.90	1.84e-08	GO:0016604	nuclear body
1.04	1.96e-08	GO:0044464	cell part
1.04	2.12e-08	GO:0005623	cell
2.55	1.01e-07	GO:0022626	cytosolic ribosome
2.43	4.56e-05	GO:0015934	large ribosomal subunit
1.91	6.24e-05	GO:0000151	ubiquitin ligase complex
1.95	1.12e-04	GO:0016607	nuclear speck
2.35	1.26e-04	GO:0000502	proteasome complex
1.26	3.24e-04	GO:0005739	mitochondrion
1.20	3.68e-04	GO:0031090	organelle membrane
2.37	8.47e-04	GO:0015935	small ribosomal subunit
2.02	1.25e-03	GO:0042470	melanosome
2.02	1.25e-03	GO:0048770	pigment granule
2.51	1.33e-03	GO:0015030	Cajal body
2.64	3.20e-03	GO:0022627	cytosolic small ribosomal subunit
2.55	4.07e-03	GO:0022625	cytosolic large ribosomal subunit
1.37	4.62e-03	GO:0005694	chromosome
2.87	6.40e-03	GO:0044452	nucleolar part
2.93	8.77e-03	GO:0005689	U12-type spliceosomal complex
1.31	1.15e-02	GO:0031967	organelle envelope
2.61	1.23e-02	GO:0030532	small nuclear ribonucleoprotein complex
1.25	1.87e-02	GO:0005794	Golgi apparatus
4.49	1.88e-02	GO:0005885	Arp2/3 protein complex
1.29	2.50e-02	GO:0031975	envelope

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.24	2.30e-37	GO:0005515	protein binding
1.81	3.46e-28	GO:0003723	RNA binding
1.11	1.08e-23	GO:0005488	binding
1.31	4.59e-20	GO:0003676	nucleic acid binding
2.31	1.07e-11	GO:0003735	structural constituent of ribosome
1.27	3.58e-09	GO:0000166	nucleotide binding
1.78	2.92e-06	GO:0019787	small conjugating protein ligase activity
1.80	3.04e-06	GO:0004842	ubiquitin-protein ligase activity
1.25	6.28e-06	GO:0035639	purine ribonucleoside triphosphate binding
1.25	7.77e-06	GO:0017076	purine nucleotide binding
1.24	1.80e-05	GO:0032553	ribonucleotide binding
1.24	1.80e-05	GO:0032555	purine ribonucleotide binding
2.27	2.47e-05	GO:0008135	translation factor activity, nucleic acid binding
1.39	2.50e-05	GO:0017111	nucleoside-triphosphatase activity
1.39	2.62e-05	GO:0016462	pyrophosphatase activity
1.38	3.79e-05	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.38	5.45e-05	GO:0016817	hydrolase activity, acting on acid anhydrides
1.65	9.84e-05	GO:0016881	acid-amino acid ligase activity
1.59	2.47e-04	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.25	2.75e-04	GO:0030554	adenyl nucleotide binding
1.25	3.33e-04	GO:0005524	ATP binding
1.47	3.41e-04	GO:0016874	ligase activity
1.24	3.84e-04	GO:0032559	adenyl ribonucleotide binding
1.11	4.34e-04	GO:0003824	catalytic activity
1.55	3.54e-03	GO:0042623	ATPase activity, coupled
1.84	6.80e-03	GO:0051082	unfolded protein binding
1.45	7.61e-03	GO:0003712	transcription cofactor activity
1.96	8.20e-03	GO:0008565	protein transporter activity
1.44	8.78e-03	GO:0000988	protein binding transcription factor activity
1.44	8.78e-03	GO:0000989	transcription factor binding transcription factor activity
1.44	2.11e-02	GO:0016887	ATPase activity
1.64	2.28e-02	GO:0008168	methyltransferase activity
1.39	2.46e-02	GO:0004674	protein serine/threonine kinase activity
2.25	2.60e-02	GO:0003743	translation initiation factor activity